takisbiotech

ANALYSIS OF TUMOR-INFILTRATING BLYMPHOCYTES FOR THE DESIGN OF NEWTHERAPEUTIC STRATEGIES BASED ONSYNTHETIC ANTIBODIES

Tumor-infiltrating lymphocytes (TILs) play a crucial role in regulating tumor progression, with T cells traditionally receiving the most attention. However, recent studies have highlighted the significant contribution of B cells to anti-tumor immunity. Research indicates that high densities of B cells and elevated antibody levels correlate with improved prognoses in various human cancers, including soft […]

AN IN-SILICO DRIVE-THROUGH FOR mAbs DISCOVERY

When monoclonal antibody development intersects with computational science, a groundbreaking collaboration emerges: this is MATCH, or Monoclonal Antibody Development and Characterization Laboratory. Leading this collaboration is our Valerio Chiarini, Ph.D., an expert in structural biology and bioinformatics, and Giuseppe Roscilli, our CTO, as part of the Rome Technopole project. The effort to identify viable candidate […]